Friday, 30 October 2009

science


Drug Discovery Kits
The Maybridge Quick2Lead Compound Kits are designed to save time and money by enabling rapid compound library synthesis around bioactive "hits" from screening assays. The kits are made up of preweighed, diverse building-block selections, facilitating rapid capture of structure-activity data from the closely related structural analogs within the library. Quick2l_ead Compound Kits are available as five functionality-based kits, with each containing 48 carefully selected compounds. This enables the exploration of a wide area of chemical space to maximize credible structure-activity data acquisition for the successful conversion of an initial hit into a genuine, optimizable lead. Because these compounds are all preweighed, the kits are ready to use by simply adding solvent and transferring to a synthesizer. The five functional groups available are carboxylic acids, sulfonyl chlorides, amines, anilines, and boronic acids.

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